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Hypoglycaemia/Hyperinsulinism

 

A blinded-unblinded study of continuous glucose monitoring in congenital hyperinsulinism

Investigator:

Indi Banerjee, indi.banerjee@mft.nhs.uk 

Maria Salomon Estebanez, maria.salomonEstebanez@mft.nhs.uk

Summary:

 

Start Date: 1 Aug 2021
End Date: 1 Aug 2022
Further Information: Updated Oct 2021

 

A UK wide study of the prevalence of hypoglycaemia by continuous glucose monitoring in patients with congenital hyperinsulinism 

Investigator:

Indi Banerjee, indi.banerjee@mft.nhs.uk 

Maria Salomon Estebanez, maria.salomonEstebanez@mft.nhs.uk

Summary:

 

Start Date: 1 Nov 2021
End Date: 1 Nov 2022
Further Information: Updated Oct 2021

  

CHART study - retrospective natural history study in patients with congenital hyperinsulinism

Investigator:

Indi Banerjee, indi.banerjee@mft.nhs.uk 

Maria Salomon Estebanez, maria.salomonEstebanez@mft.nhs.uk

Summary:

 

Start Date: 1 Dec 2021
End Date: 1 Jul 2022
Further Information: Updated Oct 2021

 

Clinical trials of dasiglucagon (ZP 103, 106, 109)

Investigator:

Indi Banerjee, indi.banerjee@mft.nhs.uk 

Maria Salomon Estebanez, maria.salomonEstebanez@mft.nhs.uk

Summary:

 

Start Date: 1 June 2018
End Date: Still active
Further Information: Updated Oct 2021

 

Web-based adherence information and nurse monitoring clinic for the use of Growth Hormone 

Investigator:

Indi Banerjee, indi.banerjee@mft.nhs.uk 

Summary:

 

Start Date: 1 Aug 2020
End Date: Still active
Further Information: Updated Oct 2021

 

 

Deep Phenotyping of congenital hyperinsulinism 

Investigator:

Mark J Dunne, mark.j.dunne@mft.nhs.uk

Summary:

 

Start Date: 1 Jan 2017
End Date: Still active
Further Information: Updated Oct 2021

 

Novel biomarkers of congenital hyperinsulinism

Investigator:

Mark J Dunne, mark.j.dunne@mft.nhs.uk

Indi Banerjee, indi.banerjee@mft.nhs.uk 

Maria Salomon Estebanez, maria.salomonEstebanez@mft.nhs.uk

Summary:

 

Start Date: 1 Jan 2021
End Date: Still active
Further Information: Updated Oct 2021

 

Congenital Hyperinsulinism NIHR BioResource

Investigator:

Mark J Dunne, mark.j.dunne@mft.nhs.uk

Summary:

 

Start Date: 1 Jan 2019
End Date: Still active
Further Information: Updated Oct 2021

 

Maximising the Hyperinsulinism Global Registry (MaxHIGR)

Investigator:

Indi Banerjee, indi.banerjee@mft.nhs.uk 

Mark J Dunne, mark.j.dunne@mft.nhs.uk

Maria Salomon Estebanez, maria.salomonEstebanez@mft.nhs.uk

Summary:

 

Start Date: 1 Jan 2019
End Date: Still active
Further Information: Updated Oct 2021

 

 

REACT Real Time Continuous Glucose Monitoring in Neonatal Intensive Care 

Investigator:

Dr Kathryn Beardsall, kb274@medschl.cam.ac.uk

Summary:

Both high and low blood sugar levels are common in preterm babies and this has been linked with poor outcome. One of the difficulties of managing sugar levels in preterm babies is that it involves a sample of blood being taken and as clinical teams try to avoid disturbing babies there is often a long time between measurements. There is now a device which monitors and records sugar levels continuously (continuous glucose monitor) which is used by some children and adults with diabetes. This involves a small sensor being placed under the skin which can be left for up to a week and allows the patient to respond quickly and treat changes in their sugar levels.

REACT will be studying the effectiveness of using continuous glucose monitoring in 200 preterm babies to see if it can help reduce how often and for how long they have very high or very low sugar levels.

Start Date: 20/06/2016
End Date: 30/11/2018
Further Information:

https://vimeo.com/224488826/133526077c

http://paediatrics.medschl.cam.ac.uk/research/clinical-trials/real-time-continuous-glucose-monitoring-newborn-react/

https://www.journalslibrary.nihr.ac.uk/programmes/eme/1113307/#/