A randomised study of two anti-thyroid drug treatment regimens in young people with thyrotoxicosis.
Aim
To compare the advantages and disadvantages of the two main anti thyroid drug treatment regimens ('block and replace' versus dose titration) for 36 months in young people with hyperthyroidism by;
determining remission rates after 4 and 6 years (i.e. 1 and 3 years post-treatment);
determining the amount of time that patients have abnormal biochemical indices whilst on treatment.
Trial status
Recruitment is ongoing with a view to recruiting 160 participants throughout the UK. Currently 79 patients have been recruited at 15 sites. Referrals are welcome…….